Researchers “stunned” by study that raises hopes for Parkinson’s treatment

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Author: Pippa Prendergast-CoatesPublished: 2 July 2020

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illustration of transmitting synapse, neuron or nerve cell

A new study reprogramming cells to replace reduced dopamine neurons in the brain could be used to reverse symptoms of Parkinson’s and other neurological conditions.

As part of the study – conducted by the University of California San Diego (UCSD) – researchers found a way to convert star-shaped brain cells called astrocytes into cells producing dopamine. The team used the method to treat mouse models of Parkinson’s, administering the treatment into the areas of the brain that typically lose dopamine producing neurons. This restored reduced dopamine production to normal levels and reversed the symptoms of Parkinson’s. The researchers will continue to optimise the therapy in other mouse models of Parkinson’s before testing it on people with the condition.

William Mobley, a neurosciences professor at UCSD, said: “I was stunned at what I saw. This whole new strategy for treating neurodegeneration gives hope that it may be possible to help even those with advanced disease.”

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For more information on the latest Parkinson’s research please visit the EPDA website.

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Researchers “stunned” by study that raises hopes for Parkinson’s treatment

News

Author: Pippa Prendergast-CoatesPublished: 2 July 2020

Prep: Cook: Serves:

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10 breakthrough Parkinson’s therapies to watch out for

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John Stapleton: “More Parkinson’s research is needed, full stop”

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“Not one of my friends realised you could get Parkinson’s disease so young”

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Is there a link between Parkinson’s disease and blood vessel dysfunction?

New swab test may help with Parkinson’s disease diagnosis

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Researchers “stunned” by study that raises hopes for Parkinson’s treatment

News

Author: Pippa Prendergast-CoatesPublished: 2 July 2020

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Share this story

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Advances

10 breakthrough Parkinson’s therapies to watch out for

Global update

John Stapleton: “More Parkinson’s research is needed, full stop”

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New swab test may help with Parkinson’s disease diagnosis

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