New study identifies possible markers of inflammation linked to Parkinson’s disease

News

Author: Scarlett SherriffPublished: 7 July 2022

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

Microglia cells

Researchers based in Germany and the US may have identified a way to detect overactivity of microglia cells – a type of brain cell known to cause inflammation in the brain that is a key sign of neurodegenerative conditions like Parkinson’s.

As part of the study, published in the journal ‘PNAS’, the researchers used mouse models of Parkinson’s and Alzheimer’s.

They measured neuroinflammation in the animals by comparing protein concentrations in a control group of healthy mice versus mice models of the condition – and found that 25 proteins were altered in those affected with Parkinson’s pathology.

In a press release, one of the study’s co-authors, Professor Mathias Jucker, said the findings could eventually lead to a “major advance”: being able to monitor inflammation in patients’ nervous systems over time. He said: “This would allow us to better understand different disease stages and also to test anti-inflammatory substances in clinical trials.”


Read more:

Heart problems linked to dementia risk in Parkinson’s disease, say researchers

A “revolutionary” step in stem cell therapy for Parkinson’s disease?

Go Back

Share this story

Comments


Related articles


sian young woman nurse at nursing home taking care of disabled senior elderly man on wheelchair. Therapist doctor measure heart rate by stethoscope on older patient. Medical insurance service concept

News

Heart problems linked to dementia risk in Parkinson’s disease, say researchers

Researchers at the University of Turin, Italy, have identified that Parkins

READ MORE

News

A new technique for isolating brain cells linked to Parkinson’s

Researchers at Carnegie Mellon University, US, have developed a new techniq

READ MORE
Visualisation software Guide-XT from Boston Scientific.

sponsored article

Advances

DBS visualisation software: a new era for Parkinson’s disease treatment?

Three experts on how the technology could change patients’ experiences

READ MORE