Researchers create Parkinson’s-resistant stem cells

News

Author: Simge Eva DoganPublished: 2 January 2019

Prep: Cook: Serves:

Scientists at the University of Edinburgh, UK, have created stem cells that they say are resistant to developing Parkinson’s.

The study – published in science journal ‘European Journal of Neuroscience’ – used gene editing techniques to remove the alpha-synuclein protein from the stem cells. To test the resistance of the new stem cells, researchers treated both edited and unedited stem cells with a chemical agent that induced Lewy bodies – abnormal proteins that lead to neurodegeneration.

The results showed that the gene-edited cells did not develop signs of Parkinson’s, whereas the unedited cells did.

Dr Tilo Kunath – who led the study – said: “We know that Parkinson’s disease spreads from neuron-neuron, invading healthy cells. This could essentially put a shelf life on the potential of cell replacement therapy. Our exciting discovery has the potential to considerably improve these emerging treatments.”

To read more on this topic click here.

For more information on Parkinson’s and stem cell therapy please visit the EPDA website.

World War II weapon antidote could treat Parkinson’s

Last Month

Next Month

Go Back

Share this story

Comments

Interviews

“There is nothing wrong with my head and I will not be judged by my condition”

The latest in our monthly series

PD in Practice

VIDEO: From diagnosis to treatment in Parkinson’s disease

Watch experts explain the benefits of deep brain stimulation

Women and Parkinson’s: “My medication only works three weeks out of four”

An honest account of menstruation, medication and symptoms

Plant-based compounds could treat chronic pain in Parkinson’s, study finds

A six-year study has found that chronic pain in people with Parkinson’s is linked to a gene involved with how the brain responds to cannabis compounds. The investigation examined why some people with the condition experience persistent pain – and the impact it has on their work, daily life and social relationships. Conducted by researchers at Manchester’s Salford Royal Foundation Trust, UK, and funded by Parkinson’s UK, it is the largest study to investigate chronic pain in people with Parkinson’s. Dr Monty Silverdale, consultant neurologist at Greater Manchester Centre, said: “This study is significant because it shows the important role of genetics in chronic pain in Parkinson’s. “Our findings suggest that cannabis-based compounds may be worth investigating as a treatment for pain in Parkinson’s.”

Could playing table tennis help reduce Parkinson’s symptoms?

Researchers at Fukuoka University, Japan, have found that playing table tennis may help alleviate motor symptoms in Parkinson’s. As part of the study, 12 people with Parkinson’s with an average age of 73 played a five-hour session of table tennis every week for a period of six months. The sessions were developed specifically for people with the condition by experienced table tennis players from the university’s department of sports science. The participants were evaluated after three months and at the end of the study. At both evaluations, participants had reduced symptoms – showing improvement in speech, handwriting, walking and hand tremors. Two participants reported side-effects of backache and falling. Study author Ken-ichi Inoue, MD, of Fukuoka University said: “While this study is small, the results are encouraging because they show ping pong, a relatively inexpensive form of therapy, may improve some symptoms of Parkinson’s disease. A much larger study is…

‘Dopamine-boosting’ BT13 molecule could be used to slow Parkinson’s

Researchers have discovered that a molecule called BT13 could have potential to treat Parkinson’s. The study, conducted by scientists from the University of Helsinki, Finland, found that mice injected with the BT13 molecule had an increase in dopamine levels in the brain. Their findings also suggested that the molecule could lead to a new drug treatment to protect the brain cells that produce dopamine. Dopamine helps coordinate movement, but people with Parkinson’s have normally lost between 70 and 80% of the brain cells that produce the neurotransmitter when they are diagnosed with the condition. Professor David Dexter, Deputy Director of Research at Parkinson’s UK – which co-funded the study – said: “People with Parkinson’s desperately need a new treatment that can stop the condition in its tracks, instead of just masking the symptoms. “More research is needed to turn BT13 into a treatment to be tested in clinical trials, to…

All fields required

First name*
Last name*
Email address*
Enter Email Confirm Email
Country of residence*
About me*
- I have Parkinson's disease
- I am a partner / carer / family / friend of someone who has Parkinson's
- I am a healthcare professional with an interest in Parkinson's
- I work for a Parkinson's disease organisation
- Other
CAPTCHA
*
- By proceeding you agree to our
Comments
This field is for validation purposes and should be left unchanged.

Researchers create Parkinson’s-resistant stem cells

News

Author: Simge Eva DoganPublished: 2 January 2019

Prep: Cook: Serves:

Last Month

Next Month

Share this story

Comments

Interviews

“There is nothing wrong with my head and I will not be judged by my condition”

sponsored article

PD in Practice

VIDEO: From diagnosis to treatment in Parkinson’s disease

Women and Parkinson's

Women and Parkinson’s: “My medication only works three weeks out of four”

Plant-based compounds could treat chronic pain in Parkinson’s, study finds

Could playing table tennis help reduce Parkinson’s symptoms?

‘Dopamine-boosting’ BT13 molecule could be used to slow Parkinson’s

{title}

Subscribe

Researchers create Parkinson’s-resistant stem cells

News

Author: Simge Eva DoganPublished: 2 January 2019

Prep: Cook: Serves:

Last Month

Next Month

Share this story

Comments

Related articles

Interviews

“There is nothing wrong with my head and I will not be judged by my condition”

sponsored article

PD in Practice

VIDEO: From diagnosis to treatment in Parkinson’s disease

Women and Parkinson's

Women and Parkinson’s: “My medication only works three weeks out of four”

Plant-based compounds could treat chronic pain in Parkinson’s, study finds

Could playing table tennis help reduce Parkinson’s symptoms?

‘Dopamine-boosting’ BT13 molecule could be used to slow Parkinson’s

{title}

Subscribe

Sign in