Researchers create Parkinson’s-resistant stem cells

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Author: Simge Eva DoganPublished: 2 January 2019

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Scientists at the University of Edinburgh, UK, have created stem cells that they say are resistant to developing Parkinson’s.

The study – published in science journal ‘European Journal of Neuroscience’ – used gene editing techniques to remove the alpha-synuclein protein from the stem cells. To test the resistance of the new stem cells, researchers treated both edited and unedited stem cells with a chemical agent that induced Lewy bodies – abnormal proteins that lead to neurodegeneration.

The results showed that the gene-edited cells did not develop signs of Parkinson’s, whereas the unedited cells did.

Dr Tilo Kunath – who led the study – said: “We know that Parkinson’s disease spreads from neuron-neuron, invading healthy cells. This could essentially put a shelf life on the potential of cell replacement therapy. Our exciting discovery has the potential to considerably improve these emerging treatments.”

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For more information on Parkinson’s and stem cell therapy please visit the EPDA website.

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Researchers create Parkinson’s-resistant stem cells

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Author: Simge Eva DoganPublished: 2 January 2019

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Researchers create Parkinson’s-resistant stem cells

News

Author: Simge Eva DoganPublished: 2 January 2019

Prep: Cook: Serves:

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Advances

10 breakthrough Parkinson’s therapies to watch out for

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Meet EPDA vice-president Susanna Lindvall as she gets involved in #UniteForParkinsons 2018

Could treadmill training improve Parkinson’s symptoms?

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New wearable device could counteract gait

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