Repurposed cancer drug shows promise for Parkinson’s

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Author: Simge Eva DoganPublished: 5 December 2018

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Researchers at the Oxford Parkinson’s Disease Centre, UK, have repurposed an experimental cancer drug – called tasquinimod – as a potential treatment for Parkinson’s.

The study – funded by Parkinson’s UK and published in science journal ‘Cell Stem Cell’ – has been tested on a total of 10 patients so far.

As part of the research, the study grew brain cells from donated skin cell samples of people living with a rare genetic form of Parkinson’s – this process was then repeated on people with a common non-genetic form of the condition. Researchers found that tasquinimod can block HDAC4, a protein that causes Parkinson’s genes to become inactive.

Professor Richard Wade-Martins, co-lead author of the study, said: “We think that switching off these genes in brain cells may play a vital role in the cell damage and death that occurs in Parkinson’s.”

To read more on this topic click here.

For more information on the latest Parkinson’s research please visit the EPDA website.

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Repurposed cancer drug shows promise for Parkinson’s

News

Author: Simge Eva DoganPublished: 5 December 2018

Prep: Cook: Serves:

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Cure3: making art for Parkinson’s research

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Rich roast pork Orloff with vegetables and red pesto

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“We know so much about Parkinson’s, but so little about people with Parkinson’s”

Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

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Repurposed cancer drug shows promise for Parkinson’s

News

Author: Simge Eva DoganPublished: 5 December 2018

Last Month

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Share this story

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Global update

Cure3: making art for Parkinson’s research

Recipes & Nutrition

Rich roast pork Orloff with vegetables and red pesto

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“We know so much about Parkinson’s, but so little about people with Parkinson’s”

Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

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