To read more on this topic click here.
Parkinson’s could be present from birth, study finds
Author: Caithlin NgPublished: 6 February 2020
Prep: Cook: Serves:
Parkinson’s may be present from birth in younger people with the condition, new research has found.
The study – conducted by Cedars-Sinai Medical Centre, US, and published in ‘Nature Medicine’ journal – used induced stem cells from people with young-onset Parkinson’s, to grow dopamine-producing neurons and observe them for early warning signs of the condition.
An abnormal pile-up of protein was found during the neurons’ development, including alpha-synuclein; which occurs in Parkinson’s. The scientists conjecture that Parkinson’s symptoms appear when the pile-up continues over 20 or 30 years.
The team also found that the drug PEP005 – currently used against skin precancers – could help treat the condition.
Michele Tagliati, vice chair and professor at Cedars-Sinai’s Department of Neurology and the study’s co-author, said: “This exciting new research provides hope that one day we may be able to detect and take early action to prevent this disease in at-risk individuals.”
Lead image credit: Clive Svendsen, PhD, director of the Cedars-Sinai Board of Governors Regenerative Medicine Institute, right, and Nur Yucer, PhD, a project scientist, discuss a microscope image of dopamine neurons. Photo by Cedars-Sinai.
For more information on the latest Parkinson’s research please visit the EPDA website.
Read more :
Share this story
How does facial masking affect people with Parkinson’s?
Find out what causes hypomimia – and how the symptom can be treatedREAD MORE
#UniteForParkinsons campaign wins ‘highly commended’ award
Parkinson’s Life and partners recognised in ‘Best Charity Campaign’ aREAD MORE
Parki’s Kookatelier: fish soup ‘a la Bouillabaisse’
'A la Bouillabaisse': A tasty seafood dishREAD MORE