Parkinson’s may originate in the gut, says new study

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Author: Joe McAweaneyPublished: 27 June 2019

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Researcher using microscope in laboratory

A new study, published in medical journal ‘Neuron’, has found evidence to suggest that Parkinson’s may originate in the gut.

As part of the study, researchers at Johns Hopkins University School of Medicine, US, injected abnormally folded alpha-synuclein – a protein closely connected to the development of Parkinson’s – into the gut of over 100 mice.

After one month the misfolded protein had spread to areas of the brain, with researchers saying the animals’ symptoms closely mirrored the condition in humans.

The results follow on from a study in Sweden in 2017, when a team of researchers at the Karolinska Institutet found similar results.

Ted Dawson, professor of neurology at Johns Hopkins University and co-author of the research said: “It supports and really provides the first experimental evidence that Parkinson’s disease can start in the gut and go up the vagus nerve.”

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For more information on the latest Parkinson’s research please visit the EPDA website.

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Parkinson’s may originate in the gut, says new study

News

Author: Joe McAweaneyPublished: 27 June 2019

Prep: Cook: Serves:

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Parkinson’s ruined my calligraphy career – but not my life

Global update

#UniteForParkinsons: the story so far

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Pesticide that increases Parkinson’s risk by 150% reapproved in the US

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Parkinson’s may originate in the gut, says new study

News

Author: Joe McAweaneyPublished: 27 June 2019

Prep: Cook: Serves:

Last Month

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Share this story

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Related articles

Perspectives

Parkinson’s ruined my calligraphy career – but not my life

Global update

#UniteForParkinsons: the story so far

Perspectives

Michael J Fox is “an inspiration to us all” for laughing at his Parkinson’s symptoms

Can tremor predict the effect of Parkinson’s disease medication?

Could a ‘Mediterranean diet’ lower the risk of Parkinson’s for women?

Pesticide that increases Parkinson’s risk by 150% reapproved in the US

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