Why Parkinson’s disease research can’t ignore sex differences

News

Author: Johanna Stiefler JohnsonPublished: 25 March 2021

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

Researchers at the University of Maryland, US, have highlighted the growing body of research that suggests male and female patients are affected differently by Parkinson’s disease.

Parkinson’s disease is caused by the death of cells in the brain and nervous system. These cellular changes are associated with the collapse of the blood-brain barrier – a border of cells that protects the brain from damaging molecules.

In the article – published in scientific journal ‘APL Bioengineering’ – the researchers observed that this barrier behaves differently in male and female patients. The fact that some research suggests women tend to have a stronger blood-brain barrier, for example, could explain why Parkinson’s disease is more common in men.

Dr Alisa Morss Clyne, one of the article’s authors, says this research has been an “awakening”. She adds: “You cannot ignore sex differences. My goal is to inspire people to include sex differences in their research.”


Read more:

“Recognising gender difference is essential for Parkinson’s research”

“We are not just variants of men”

Go Back

Share this story

Comments


Related articles


Advances

New brain chemical pump is “huge step forward” for advanced Parkinson’s

Approval of new dopamine pump welcomed by campaigners

READ MORE
Monkey with Parkinson's

Advances

Scientists genetically engineer world’s first monkey with Parkinson’s disease

Controversial research in Japan could lead to breakthroughs

READ MORE
Angela Merkel

Global update

Angela Merkel sparks health concerns

The German chancellor was seen shaking at a recent event

READ MORE