New study links missing piece of DNA in Parkinson’s patients to genetic disorder

News

Author: Parkinson's Life editorsPublished: 4 May 2016

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

News image

Researchers have found a link between Parkinson’s disease and a genetic disorder that can cause heart defects, palatal abnormalities and learning disabilities.

The team at University College London, Institute of Neurology, has discovered the same chromosome deletion – known as ‘22q’ – that occurs in DiGeorge syndrome also exists in Parkinson’s disease.

This particular ‘chromosome deletion’ has up until now normally been associated with DiGeorge syndrome, which is usually noticeable at birth and can cause heart defects, problems with the mouth, feeding and hearing, and multiple other diseases.

Professor Nicholas Wood, consultant neurologist and neuroscience programme director of UCLH NIHR Biomedical Research Centre, said: “Our findings suggest there may be some Parkinson’s patients who also have undiagnosed DiGeorge disease. Interestingly, this deletion has also been reported in schizophrenia, which, like Parkinson’s, involves dopamine signalling. The potential links and common pathophysiological mechanisms are very exciting indeed.”

Go Back

Share this story

Comments


Related articles


Advances

Parkinson’s UK to launch largest plant-based oil trial in the world

The trial will be carried out over three years

READ MORE
Atlantic Ocean Row Liz Dennett

Interviews

“I’m ready to row, eat, sleep and repeat”

We hear from the woman taking on the Atlantic Ocean

READ MORE
roast-pork-orloff

Recipes & Nutrition

Rich roast pork Orloff with vegetables and red pesto

A hearty pork dish, layered with cheeses & seasoned with red pesto

READ MORE