Can negative dreams predict long-term cognitive decline in Parkinson’s?

News

Author: Pippa Prendergast-CoatesPublished: 20 August 2020

Prep: Cook: Serves:

New research has suggested that negative emotions in dreams are associated with a long-term decline in cognitive function in people living with Parkinson’s.

The study, conducted by researchers in Portugal, asked 58 individuals to record a dream diary for a fortnight. Participants were assessed on motor and non-motor symptoms with a cognitive screening tool called the Montreal Cognitive Assessment (MoCA). After four years, MoCA scores significantly decreased indicating lower cognitive function, particularly in those who had experienced negative emotions while dreaming. This suggests the content of dreams may independently predict cognitive decline long-term.

Researchers say the findings show “a significant, positive and independent association between negative emotions in dreams and a reduction in MoCA scores after four years”, but that the findings should be considered preliminary at this stage due to the small sample size.

To read more on this topic click here.

For more information on the latest Parkinson’s research please visit the EPDA website.

Can over-the-counter drugs reduce risk of developing genetic Parkinson’s?

Last Month

Next Month

Go Back

Share this story

Comments

Global update

Billy Connolly’s best Comic Relief moments

After his emotional appeal, we look at Billy's top fundraising moments

Global Parkinson’s song competition

Have your piece performed at the opening ceremony

6 more world-class wildlife stills from a photographer with Parkinson’s

David Plummer shares more of his top photographs of wildlife in action

Study suggests why neurons die in Parkinson’s disease

Researchers at the University of Córdoba, Spain, have discovered how a certain protein may be linked to death of dopamine-producing neurons associated with Parkinson’s. Using animal models of the condition to conduct their study, the team focused on the protein DJ-1 – whose link to Parkinson’s has previously been established, though its exact function was uncertain. The researchers compared neurons in the brains of mice that possessed the gene expressing DJ-1 with those that did not. The findings revealed that dysfunction or absence of the gene expressing the DJ-1 protein could trigger the ‘cell cycle’ (the process by which cells divide), which should not occur under normal conditions. Because neurons lack the capacity to divide, this causes them die – leading to the onset of symptoms linked with Parkinson’s. It is hoped that uncovering these details about the relationship between DJ-1’s absence and Parkinson’s may lead to the development of…

Researchers have finally identified brain cells linked to Parkinson’s disease

For decades, scientists have known that Parkinson’s is associated with the death of dopamine-producing cells in the brain. Now, researchers from the Broad Institute of MIT and Harvard, US, have discovered the specific subtype of brain cells that die in Parkinson’s disease. Using a technique called single-cell RNA signalling, which enables the individual analysis of cells within a tissue for activity and protein production, researchers identified 10 subtypes of dopamine-producing cells within the donated brains of people who died from causes unrelated to Parkinson’s. The team carried out the same investigation on people who had died with Parkinson’s or a condition with similar symptoms called Lewy body dementia. They discovered that only one subtype of the cells had reduced in number – which suggests many of these cells had died while the people were living. It is hoped that the findings could lead to better understanding of Parkinson’s causes and…

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

In an innovative trial by North Bristol NHS Trust, UK, surgeons have succeeded in implanting a tiny deep brain stimulation (DBS) device into a person’s skull. Their aim? To address symptoms of Parkinson’s. Designed with a tiny battery system that is inserted into the skull, the DBS device delivers electric impulses to targeted areas of the brain through electric probes. In doing so, it works to address abnormal brain cell activity associated with Parkinson’s – and may help to ease symptoms. One of around 25 patients selected for the year-long trial has described the device’s impact as “amazing”. Commenting on the results of the trial so far, consultant neurologist Dr Alan Whone of North Bristol NHS Trust said: “We are hopeful that if these findings hold up, we will have a significant technical advance by which to improve Parkinson’s care across the world.”

All fields required

First name*
Last name*
Email address*
Enter Email Confirm Email
Country of residence*
About me*
- I have Parkinson's disease
- I am a partner / carer / family / friend of someone who has Parkinson's
- I am a healthcare professional with an interest in Parkinson's
- I work for a Parkinson's disease organisation
- Other
CAPTCHA
*
- By proceeding you agree to our
Phone
This field is for validation purposes and should be left unchanged.

Can negative dreams predict long-term cognitive decline in Parkinson’s?

News

Author: Pippa Prendergast-CoatesPublished: 20 August 2020

Prep: Cook: Serves:

Last Month

Next Month

Share this story

Comments

Global update

Billy Connolly’s best Comic Relief moments

Global update

Global Parkinson’s song competition

Perspectives

6 more world-class wildlife stills from a photographer with Parkinson’s

Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

{title}

Subscribe

Can negative dreams predict long-term cognitive decline in Parkinson’s?

News

Author: Pippa Prendergast-CoatesPublished: 20 August 2020

Last Month

Next Month

Share this story

Comments

Related articles

Global update

Billy Connolly’s best Comic Relief moments

Global update

Global Parkinson’s song competition

Perspectives

6 more world-class wildlife stills from a photographer with Parkinson’s

Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

{title}

Subscribe

Sign in