For a collection of the latest Parkinson’s-related research papers please visit the EPDA website here.
Mouse study suggests neurodegenerative disease begins soon after birth
Author: Parkinson's Life editorsPublished: 22 May 2018
Prep: Cook: Serves:
A study published in the ‘Journal of Clinical Investigation’ has suggested mechanisms that lead to Parkinson’s in adulthood, may begin much earlier than previously thought.
The study, carried out by Northwestern University, Illinois, US, researched movement disorder spinocerebellar ataxia type 1 by genetically engineering a mouse to mirror the human disease.
Researchers found that altering circuity in the cerebellum – an area of the brain that controls movements – set the stage for later susceptibility to neurological disease.
Professor Puneet Opal, who worked on the study, said: “This is the first discovery of alterations in an adult-onset spinocerebellar disorder that stems from such early developmental processes.
“This may well be generalisable to a whole host of other diseases, including Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis.”
Share this story
Parkinson’s AI trial launched by Chinese tech giant
The study will take place in LondonREAD MORE
John Lehr: “I’m inspired by the persistent hope of those living with Parkinson’s”
PDF CEO unveils plans for organisation’s 60th anniversary yearREAD MORE
Sign up to be part of ‘world-first’ global health study into Parkinson’s disease
Innovative smartphone app to gather data for global health studyREAD MORE