Michael J Fox Foundation announces 2017 highlights

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Author: Parkinson's Life editorsPublished: 4 January 2018

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The Michael J Fox Foundation has announced that it provided US$80 million in funding to over 240 investigators from academia, biotechnology, pharmaceuticals and governments in 2017.

The organisation, which was founded in 2000 by the actor and person with Parkinson’s Michael J Fox, has funded a range of projects, focusing on: investigating Parkinson’s biological pathways, laboratory tools to accelerate Parkinson’s research, and growing the online Fox Insight study.

The foundation also shared the significant research progress that was made in 2017, such as the advancement of alpha-synuclien clinical trials, the release of new drugs to manage motor symptoms and the emergence of key technologies that provide insights to scientists.

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Ireland survey aims to uncover link between pesticides and Parkinson’s disease

Previous studies of vineyard and agricultural workers in France and the US highlight potential correlations between pesticide exposure and Parkinson’s risk. Now, a team is conducting the first study in Ireland to investigate this potential link. Last week, researchers from University College Cork, Ireland, took to the country’s National Ploughing Championships – a three-day country show, agricultural trade fair and ploughing competition. Their goal? To “gather information on the environmental risks associated with Parkinson’s in Ireland”, according to Professor Aideen Sullivan of the university’s Department of Anatomy and Neuroscience. “Our survey is a broad-stroke approach. We are going to ask people what categories of pesticides they’ve used,” said Sullivan’s colleague, Dr Lucy Collins-Stack. “We are going into this thinking there may be a stronger link with rural settings rather than towns, but we still want to look at both.” The survey can be completed online.

Is there a link between Parkinson’s disease and blood vessel dysfunction?

Scientists in Slovakia have investigated the link between blood vessel dysfunction and Parkinson’s – and found that dopamine agonists may have an impact. The team studied the function of the endothelium – a membrane which lines the heart and blood vessels and helps control blood fluidity – in 41 people with the condition and 41 people without. Endothelial function was then measured through a parameter that assessed how easily blood could flow through the vessels. The results showed that while more people with Parkinson’s had endothelial dysfunction compared to those without, the difference did not reach statistical significance. However, the researchers noted that the findings suggested “an association between smoking, dopamine agonists, and impaired endothelial function” in those with the condition. Outlining the study’s limitations, the team noted that more research is needed to explore this potential link.

New swab test may help with Parkinson’s disease diagnosis

Researchers at the University of Manchester, UK, have drawn on one woman’s sense of smell to develop a swab test that may be used to detect Parkinson’s. The scientists used the test to analyse sebum (a type of oily substance on the skin) in 79 people with Parkinson’s and a control group of 71 healthy individuals. The team identified more than 4,000 different compounds in the participant samples – including 500 that were unique to those living with the condition. The test was developed with the help of Joy Milne from Perth, Scotland, whose unique sense of smell meant that she noticed a change in her late husband Les’s odour twelve years before he was diagnosed with Parkinson’s. Speaking to the BBC, Professor Perdita Barran, who led the research, described the test as potentially “transformative” – and said that the team hopes to roll the test out to people in…

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Michael J Fox Foundation announces 2017 highlights

News

Author: Parkinson's Life editorsPublished: 4 January 2018

Prep: Cook: Serves:

Last Month

Next Month

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Interviews

“Even Muhammad Ali had a learning curve”

In my country

‘People believe a witch doctor will cure them’

Health & Fitness

Dreaming with their feet – ballet programme for PwPs

Ireland survey aims to uncover link between pesticides and Parkinson’s disease

Is there a link between Parkinson’s disease and blood vessel dysfunction?

New swab test may help with Parkinson’s disease diagnosis

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Michael J Fox Foundation announces 2017 highlights

News

Author: Parkinson's Life editorsPublished: 4 January 2018

Last Month

Next Month

Share this story

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Interviews

“Even Muhammad Ali had a learning curve”

In my country

‘People believe a witch doctor will cure them’

Health & Fitness

Dreaming with their feet – ballet programme for PwPs

Ireland survey aims to uncover link between pesticides and Parkinson’s disease

Is there a link between Parkinson’s disease and blood vessel dysfunction?

New swab test may help with Parkinson’s disease diagnosis

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