Jewish people with Crohn’s disease more likely to carry LRRK2 gene mutation

News

Author: Parkinson's Life editorsPublished: 7 February 2018

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

Rotating DNA, Genetic engineering scientific concept, blue tint, 3d rendering

A scientific study has concluded that there may be a link between Parkinson’s and Crohn’s disease within the Ashkenazi Jewish community.

The study’s findings, which were published in the journal ‘Science Translational Medicine’, has found that members of the population with Crohn’s disease are more likely to carry the LRRK2 mutation which is a significant cause of Parkinson’s.

Lead researcher Dr Inga Peter, professor of genetics and genomic sciences at the Icahn School of Medicine, New York, US, said: “Crohn’s disease is a complex disorder with multiple genes and environmental factors involved, which disproportionately affects individuals of Ashkenazi Jewish ancestry.

“The presence of shared LRRK2 mutations in patients with Crohn’s disease and Parkinson’s disease provides refined insight into disease mechanisms and may have major implications for the treatment of these two seemingly unrelated diseases.”

For more information about this research, please visit the EPDA website.

Go Back

Share this story

Comments


Related articles


Advances

New patient-centred study will harvest data via smartphones

New iPhone app could gather data of 20,000 patients

READ MORE
drawing

Interviews

‘My Dad: his Parkinson’s through my 9-year-old eyes’

We talk to the man who sketches his Parkinson’s symptoms

READ MORE
Faii-ong-gyroglove-lead

Advances

Tremor-reducing GyroGlove set to launch in 2017

Volunteer testers wanted as launch date nears

READ MORE