Genetic variation may determine physical symptoms in Parkinson’s patients

News

Author: Parkinson's Life editorsPublished: 15 April 2016

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

News image

Researchers have discovered a site of genetic variation that determined which patients with Parkinson’s disease are more likely to have tremors versus those with difficulty with balance and walking.

The team of researchers at the Perelman School of Medicine and other institutions also found that patients with this genetic variation had a slower rate of disease progression, and lower amounts of alpha-synuclein in the brain – the protein that plays a role in the development of the condition.

Clinicians have long noted that the presence of tremors, rather than balance and walking problems, as the initial or dominant symptom of Parkinson’s may suggest slower progression of the disease. The study is one of the first to link this difference to a specific genetic variation.

Christine Cooper, lead researcher, said: “This finding gives us information for the first time that has implications for diagnosis, prognosis, treatment, and prevention efforts.”

Go Back

Share this story

Comments


Related articles


Resources & Tools

Peace of mind: your Parkinson’s passport to a more comfortable holiday

‘Parkinson’s passport’ makes travelling easier

READ MORE
WPC 2016

Interviews

Meet Andy Butler, the man behind the Parkinson’s People Facebook group

One of Facebook’s largest independent Parkinson’s groups

READ MORE
potato with cream of the cream cheese and salted salmon

Recipes & Nutrition

One-day menu for people with Parkinson’s featuring salmon baked potatoes

One-day menu ideas for easy-to-chew meal planning

READ MORE