To read more on this topic click here.
Genetic database gives hope for potential Parkinson’s treatment
Author: Saskia MairPublished: 4 June 2020
Prep: Cook: Serves:
The Genome Aggregation Database (gnomAD) – the world’s largest public database of variations in DNA which can cause diseases – has given scientists hope for a potential Parkinson’s treatment.
UK and US researchers from Imperial College London, the Broad Institute of MIT and Harvard, 23andMe and the Michael J. Fox Foundation used gnomAD to study variants in the LRRK2 gene, which increases the risk of Parkinson’s. Previous studies have shown that blocking the protein formed by the gene can lead to organ damage in animals – but the scientists now suggest this approach should be safe for humans.
Research fellow Dr Nicky Whiffin said: “Large genetic databases are increasingly giving us a powerful insight into the likely impact of certain drugs. If we see that genetic variants that naturally reduce the amount of protein in our body do not result in severe diseases, we can be more confident that targeting that protein therapeutically will also be safe.”
For more information on the latest Parkinson’s research please visit the EPDA website.
Share this story
Misdiagnosed with Parkinson’s: why access to specialist neurologists is essential
What happens when your Parkinson’s diagnosis is actually wrongREAD MORE
“The world needs to know about Parkinson’s”
Meet the president of the European Parkinson’s Disease AssociationREAD MORE
How New York inspired Copenhagen to walk for Parkinson’s
‘Exercise is medicine’: the Danish Parkinson’s Association’s mottoREAD MORE