Fruit flies help shed light on development of Parkinson’s disease

News

Author: Parkinson's Life editorsPublished: 13 June 2017

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

News image

A study carried out by medical students from Juntendo University in Tokyo, Japan, has found that a loss of mitochondrial protein can exacerbate the progression of Parkinson’s disease.

The research centred on the study of mutant fruit flies. The team examined what happened to the flies that lacked mitochondrial protein CHCHD2 – a protein that plays a key role in maintaining the structure of cells.

The study found that the lack of CHCHD2 led to motor dysfunctions, such as the loss of climbing ability, as the flies aged. However, when researchers introduced a form of human CHCHD2 to the flies, the dysfunctions were reversed.

The researchers, led by medical students Hongrui Meng and Chikara Yamashita, said their results shed light on the role of CHCHD2 mutations in Parkinson’s and offer “potential therapeutic targets in Parkinson’s caused by mitochondrial dysfunction.”

Go Back

Share this story

Comments


Related articles


Vital nutrition Parkinson's recipe

Recipes & Nutrition

Nutrition-packed summer recipe for people with Parkinson’s

Nutritional therapist shares a two-course recipe

READ MORE

Special reports

Ask the expert: How will Brexit affect Parkinson’s drugs and research?

Dr Kieran Breen on the supply and manufacture of medication

READ MORE
kinetics-lead

Europe

An inspiring play about Parkinson’s and Parkour is coming to a theatre near you

What can a teenage boy and woman with Parkinson’s have in common?

READ MORE