Excess calcium in brain could cause Parkinson’s

News

Author: Parkinson's Life editorsPublished: 1 March 2018

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

Bottles of milk

Researchers at the University of Cambridge, UK, have discovered that excess levels of calcium in brain cells may lead to the formation of the toxic clusters that signify Parkinson’s disease.

The findings, reported in the journal ‘Nature Communications’, show that calcium can influence the interaction between small membranous structures inside nerve endings, which are important for neuronal signaling in the brain, and alpha-synuclein – the protein associated with Parkinson’s disease.

Dr Janin Lautenschläger, the paper’s first author, said: “This is the first time we’ve seen that calcium influences the way alpha-synuclein interacts with synaptic vesicles. We think that alpha-synuclein is almost like a calcium sensor. In the presence of calcium, it changes its structure and how it interacts with its environment, which is likely very important for its normal function.”

Go Back

Share this story

Comments


Related articles


Portugal bootcamp

Health & Fitness

Parkinson’s ‘bootcamp’ puts patients through their paces

Exercise is the order of the day in Portugal’s summer camp

READ MORE
Kathrynne Holden food groups

Recipes & Nutrition

How to choose the best nutrient-rich foods for Parkinson’s

Expert guide: foods that could help your Parkinson’s symptoms

READ MORE

Global update

Australian campaigners get moving for Parkinson’s

Thousands in Australia get set for one of the biggest events of the year

READ MORE