
Perspectives
Billy Connolly “doing really well, funny as ever,” says wife
Pamela Stephenson gives an update on her husband’s condition
READ MOREA recent study by The Scripps Research Institute, in the journal ‘Cell Reports’, shows how a process in nerve cells called the S-nitrosylation (SNO) reaction – which can be caused by ageing, pesticides and pollution – may contribute to Parkinson’s disease.
Previous studies had shown that inherited mutations to the gene PINK1 could cause young-onset Parkinson’s.
Professor Stuart Lipton, clinical neurologist at the University of California, San Diego, School of Medicine, said: “The new finding gives us a clue as to where to intervene.
“The Formation of PINK-SNO is definitely harmful to nerve cells in the Parkinson’s brain.”
Lipton’s team found that ‘SNO-ing’ appears to occur early in disease progression – early enough that intervention may be able to save brain function.
Professor Lipton continued: “The take-home message here is that the environment may affect you based on your individual genetics, and thus both are influential in causing diseases like Parkinson’s.”
Pamela Stephenson gives an update on her husband’s condition
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