Environment and genetics could be key factors in causing Parkinson’s

News

Author: Parkinson's Life editorsPublished: 29 November 2017

Parkinson's LifePrep: Parkinson's LifeCook: Parkinson's LifeServes:

3D render of a medical DNA background

A recent study by The Scripps Research Institute, in the journal ‘Cell Reports’, shows how a process in nerve cells called the S-nitrosylation (SNO) reaction – which can be caused by ageing, pesticides and pollution ­– may contribute to Parkinson’s disease.

Previous studies had shown that inherited mutations to the gene PINK1 could cause young-onset Parkinson’s.

Professor Stuart Lipton, clinical neurologist at the University of California, San Diego, School of Medicine, said: “The new finding gives us a clue as to where to intervene.

“The Formation of PINK-SNO is definitely harmful to nerve cells in the Parkinson’s brain.”

Lipton’s team found that ‘SNO-ing’ appears to occur early in disease progression – early enough that intervention may be able to save brain function.

Professor Lipton continued: “The take-home message here is that the environment may affect you based on your individual genetics, and thus both are influential in causing diseases like Parkinson’s.”

Go Back

Share this story

Comments


Related articles


Perspectives

Billy Connolly “doing really well, funny as ever,” says wife

Pamela Stephenson gives an update on her husband’s condition

READ MORE
umotif-100-for-parkinsons-app-lead

Special reports

100 for Parkinson’s: patients suffer lower moods, higher stress levels and poorer sleep quality

Latest findings from 100 for Parkinson’s study released

READ MORE
vegetarian-chilli-sin-carne

Recipes & Nutrition

Slow-cooked vegetarian chilli ‘sin carne’ with aubergine

Try this deliciously rich chilli con carne – without the 'carne'

READ MORE