Diet, nutrition and Parkinson’s: what you need to know
Recipes & Nutrition
Author: Caithlin NgPublished: 14 May 2020
Prep: Cook: Serves:
From the benefits of a Mediterranean diet to the best foods to take medication with, we share highlights from a recent webinar on ‘Nutrition – the emerging role of diet and Parkinson’s’
Diet and nutrition have been found to play a crucial role in Parkinson’s. In a recent ‘Ending Parkinson’s Disease: Live’ webinar, Parkinson’s expert Dr Bastiaan Bloem, epidemiologist Dr Alberto Ascherio and Parkinson’s campaigner Omotola Thomas, considered how different foods can affect the risk of diagnosis, maintaining bowel health and more.
We share five key takeaways from their discussion.
1. Which foods can affect your risk of developing Parkinson’s?
Diet, said Dr Bloem, “is a really hot topic in the field
of Parkinson’s”. Alongside exercise, diet and nutrition “are the big new kids
on the block when it comes to improving symptoms, and perhaps, slowing down the
progression of the disease.”
Dr Bloem and Dr Ascherio praised the Mediterranean diet, which varies by country and region, for its potential to lower the risk of developing Parkinson’s. The Mediterranean diet is generally high in vegetables, fruits, grains, healthy fats and fish, and is typically low in meat and dairy. Such a diet is rich in nutrients and antioxidants, making it “better than the traditional Western diet”, according to Dr Ascherio.
On the other hand, Dr Bloem theorised that “a lifetime of
exposure to dairy” is associated with a higher risk of developing Parkinson’s,
likely due to the pesticides ingested by cattle from contaminated grass.
Dr Ascherio added: “I don’t think that globally, dairy products are known to be a major cause of pesticide exposure. Dairy also has other effects like reducing the level of uric acid in blood, which we found to be related to a risk of Parkinson’s disease.”
2. Could you be malnourished if you have Parkinson’s?
While Dr Bloem pointed out that a regular diet should
offer all the necessary nutrients, he did note that vitamin D and vitamin C can
be exceptions. “Many people, particularly when you age and particularly when
you’re a woman, are at risk of developing a vitamin D deficiency. There are
fascinating anecdotal reports of people taking vitamin D and experiencing
improved motor symptoms.”
Meanwhile, he explained, vitamin C supplements can help to
prevent bladder infections in Parkinson’s patients by acidifying the urine. “Bladder
infections can trigger a cascade that leads to worsening Parkinson’s symptoms.”
Dr Bloem also debunked the use of supplements like vitamin E, curcumin and Coenzyme Q190, which have been found to offer no benefits to people with Parkinson’s.
3. How can you maintain your bowel health?
Bowel problems are common in Parkinson’s patients, which
Dr Bloem said can be alleviated by drinking a lot of water and eating a diet
rich in fibres. People with Parkinson’s should see their general practitioner
for laxatives only if all else fails. “The rule is you need to have bowel
movements at least once every other day.”
Thomas added: “I have a three litre water bottle that I finish by the end of the day. It is a challenge, but I try to finish it. Because I struggle very greatly with constipation, I take three or four ounces of prune juice in the morning and that seems to help me.”
4. How should you take your Parkinson’s medication?
As food can interfere with the efficacy of levodopa
medication, Dr Bloem recommended taking levodopa at least half an hour before
or after a meal. In particular, he advised that protein intake be spread across
“For most patients, taking your medication with a protein
rich meal including dairy products and meat, can reduce gastrointestinal absorption
of your levodopa. So, you need the proteins in order to keep up your muscle
strength and avoid weight loss but try to spread the proteins over the day.”
Thomas acknowledged that this can be hard to do. She said:
“I have a struggle spreading my proteins with my levodopa because I can’t take
more than 15mg of levodopa at a time, so I’m taking it every two hours.
“That is one of those things whereby theoretically, I know what I’m supposed to do, but practically, I’m not able to.”
5. Should a dietician be part of your standard Parkinson’s care?
Yes, said Dr Bloem. “I think paying attention to the gut
is part of routine clinical care at every consultation for people with
Parkinson’s. Parkinson’s starts in the gut for many patients and slow bowel
movements are very common, impacting the efficacy of your medication and
appetite for food. It needs attention.”
While a Parkinson’s doctor or nurse can offer useful
dietary advice, Dr Bloem himself recommends that his patients see a dietician
at least once. “I think it’s part of standard care.”
Watch the full webinar:
Need to know
Dr Bastiaan Bloem is a professor of neurology and director of the Parkinson’s Centre of Excellence at Radboud University Medical Centre, the Netherlands, and co-author of ‘Ending Parkinson’s Disease: A Prescription for Action’, in which experts outline a bold plan to “prevent, advocate, care and treat” Parkinson’s.
Dr Alberto Ascherio is a professor of epidemiology and nutrition at the Harvard T. H. Chan School of Public Health, US,
Omotola Thomas was diagnosed with young-onset Parkinson’s in 2016. She is a mother, blogger, Parkinson’s campaigner and founder of ParkinStand – a platform designed to encourage people to fight Parkinson’s through physical and mental activities.
For more information about Parkinson’s and healthy eating, please visit the EPDA website.
This month’s top Parkinson’s news stories from around the globe
4 days ago
New insights on immune cell process and Parkinson’s disease
Insoluble clumps of the protein alpha-synuclein, which can cause damage to brain cells, have been previously linked to Parkinson’s. Now, scientists in Germany, France and the US have uncovered new details on how brain cells respond to these clusters. The researchers discovered that the brain’s immune cells may be able to join together to break down the protein clumps. According to a press release, this was previously unknown. They also found that these neighbouring cells share mitochondria – structures that generate energy for chemical reactions – to help one another. In certain mutations associated with Parkinson’s, this process may be impaired. The researchers hope this insight could inform the development of new therapies. “We have opened the door to a field that will certainly engage researchers for many years to come,” said Professor Dr Michael Heneka, director of the Department of Neurodegenerative Diseases and Geriatric Psychiatry at the University Hospital…
Could analysing skin oil help diagnose Parkinson’s disease?
Parkinson’s disease patients tend to have high levels of oil, known as sebum, on their skin’s surface. Now, a study has suggested that analysing this substance may help when diagnosing the condition. The study revealed that sebum contains significant amounts of genetic material, specifically the molecule ribonucleic acid (RNA). Analysis of RNA contained in sebum – that is, skin surface lipids RNA, or SSL-RNA – could offer insights into a person’s health. Researchers in Japan examined SSL-RNA in men and women with and without Parkinson’s. The results suggested that the SSL-RNA profiles of those with Parkinson’s had “different characteristics” than those without. The researchers then tested whether examining these profiles with machine learning could reveal those who had Parkinson’s – and who didn’t. The team’s algorithm indicated a “relatively robust discriminatory ability,” supporting the further use of SSL-RNA as part of a future “non-invasive” method for diagnosis.
‘Sonic hedgehog’ protein could impact Parkinson’s disease dyskinesia
Dyskinesia is often caused by extended use of the common Parkinson’s medication levodopa – and can be debilitating for those with the condition. Now, researchers in the US may have found a way to suppress these involuntary movements through a protein called ‘sonic hedgehog’. To conduct their study, the team administered levodopa and sonic hedgehog agonists to rodent and non-human primate models of the condition. The results revealed that dopamine neurons use the protein to communicate with other neurons thought to play a role in levodopa-induced dyskinesia. Increased signalling of sonic hedgehog pathways was found to reduce this dyskinesia – providing “novel insight” into its formation and a “potential therapeutic solution”. “What we find,” wrote corresponding study author Professor Andreas Kottmann, “is that in several animal models, by replacing … dopamine together with agonists that mimic the effects of sonic hedgehog, these dyskinesias can be very much suppressed.”