Could scientists develop a drug to prevent Parkinson’s disease?

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Author: Sarah McGrathPublished: 16 December 2021

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Scientists at the University of Bath, UK, have refined a molecule that has potential to be developed into a drug to help prevent Parkinson’s, a study suggests.

The study explored the brain protein alpha-synuclein, which can build up and harm dopamine-producing brain cells – triggering the onset of Parkinson’s. The scientists built their study on previous analysis of short chains of amino acids (knows as peptides), tweaking a peptide called 4554W which showed potential to prevent alpha-synuclein from turning into a toxic form. It is hoped that the molecule’s new version, 4654W(N6A), may help in the development of a future preventive drug.

“A lot of work still needs to happen, but this molecule has the potential to be a precursor to a drug,” said Professor Jody Mason, who led the research. “We hope to develop a drug that can return people to good health even before symptoms develop.”

Find out more about the study on molecules and Parkinson’s disease.

For more information on the latest Parkinson’s disease research, visit Parkinson’s Europe website.

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Could scientists develop a drug to prevent Parkinson’s disease?

News

Author: Sarah McGrathPublished: 16 December 2021

Prep: Cook: Serves:

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Could scientists develop a drug to prevent Parkinson’s disease?

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Author: Sarah McGrathPublished: 16 December 2021

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Ask the expert: How close are we to a cure for Parkinson’s disease?

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