Parkinson's Life

Global update

Addressing inclusivity in Parkinson’s disease studies
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Health & Fitness

Top tips from sex therapist Gila Bronner and nurse consultant Orna Moore
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Global update

This month’s Parkinson’s stories from around the globe
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Sex, intimacy and Parkinson’s disease: an expert guide

Top tips from sex therapist Gila Bronner and nurse consultant Orna Moore

A patient and health care professional sit together.

“Researchers should regard patient participation as vital”

Addressing inclusivity in Parkinson’s disease studies

Guy Deacon standing in Erg Chebbi, Morocco

“The best way of combatting Parkinson’s disease is to do something about it”

Why Colonel Guy Deacon is travelling across Africa to raise awareness

A filmmaker’s “love letter” to Hollywood star Valerie Perrine

Stacey Souther shares what inspired his short documentary

The Orchestra Study: investigating a new Parkinson’s disease drug

Would you take part in the UCB research trial?

“It’s so important to be clear about how people can help you”

Ingrid Roesner on speaking up with Parkinson’s disease

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Study suggests why neurons die in Parkinson’s disease

Researchers at the University of Córdoba, Spain, have discovered how a certain protein may be linked to death of dopamine-producing neurons associated with Parkinson’s. Using animal models of the condition to conduct their study, the team focused on the protein DJ-1 – whose link to Parkinson’s has previously been established, though its exact function was uncertain. The researchers compared neurons in the brains of mice that possessed the gene expressing DJ-1 with those that did not. The findings revealed that dysfunction or absence of the gene expressing the DJ-1 protein could trigger the ‘cell cycle’ (the process by which cells divide), which should not occur under normal conditions. Because neurons lack the capacity to divide, this causes them die – leading to the onset of symptoms linked with Parkinson’s. It is hoped that uncovering these details about the relationship between DJ-1’s absence and Parkinson’s may lead to the development of…

Researchers have finally identified brain cells linked to Parkinson’s disease

For decades, scientists have known that Parkinson’s is associated with the death of dopamine-producing cells in the brain. Now, researchers from the Broad Institute of MIT and Harvard, US, have discovered the specific subtype of brain cells that die in Parkinson’s disease. Using a technique called single-cell RNA signalling, which enables the individual analysis of cells within a tissue for activity and protein production, researchers identified 10 subtypes of dopamine-producing cells within the donated brains of people who died from causes unrelated to Parkinson’s. The team carried out the same investigation on people who had died with Parkinson’s or a condition with similar symptoms called Lewy body dementia. They discovered that only one subtype of the cells had reduced in number – which suggests many of these cells had died while the people were living. It is hoped that the findings could lead to better understanding of Parkinson’s causes and…

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

In an innovative trial by North Bristol NHS Trust, UK, surgeons have succeeded in implanting a tiny deep brain stimulation (DBS) device into a person’s skull. Their aim? To address symptoms of Parkinson’s. Designed with a tiny battery system that is inserted into the skull, the DBS device delivers electric impulses to targeted areas of the brain through electric probes. In doing so, it works to address abnormal brain cell activity associated with Parkinson’s – and may help to ease symptoms. One of around 25 patients selected for the year-long trial has described the device’s impact as “amazing”. Commenting on the results of the trial so far, consultant neurologist Dr Alan Whone of North Bristol NHS Trust said: “We are hopeful that if these findings hold up, we will have a significant technical advance by which to improve Parkinson’s care across the world.”

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“Researchers should regard patient participation as vital”

Sex, intimacy and Parkinson’s disease: an expert guide

Parkinson’s in the news: April

Global update

Health & Fitness

Global update

Health & Fitness

Sex, intimacy and Parkinson’s disease: an expert guide

Global update

“Researchers should regard patient participation as vital”

Interviews

“The best way of combatting Parkinson’s disease is to do something about it”

Global update

A filmmaker’s “love letter” to Hollywood star Valerie Perrine

Advances

The Orchestra Study: investigating a new Parkinson’s disease drug

Women and Parkinson's

“It’s so important to be clear about how people can help you”

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Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

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“Researchers should regard patient participation as vital”

Sex, intimacy and Parkinson’s disease: an expert guide

Parkinson’s in the news: April

Global update

Health & Fitness

Global update

Health & Fitness

Sex, intimacy and Parkinson’s disease: an expert guide

Global update

“Researchers should regard patient participation as vital”

Interviews

“The best way of combatting Parkinson’s disease is to do something about it”

Global update

A filmmaker’s “love letter” to Hollywood star Valerie Perrine

Advances

The Orchestra Study: investigating a new Parkinson’s disease drug

Women and Parkinson's

“It’s so important to be clear about how people can help you”

{categories}

{title}

Study suggests why neurons die in Parkinson’s disease

Researchers have finally identified brain cells linked to Parkinson’s disease

Tiny DBS implant shows potential to advance Parkinson’s disease treatment

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